Many factors regulate a person's weight. The metabolism dictates the rate at which food is converted to fuel substrates. The sympathetic nervous system (SNS) stores and releases fat burning molecules known as catecholamines. Thermogenesis, the receiver of the SNS signal, converts fatty acids to heat. This prevents fat storage. The messenger hormone leptin controls the hunger switch. Receiver of the leptin message, the brain tells us when to eat, how much to eat and when to stop eating.
Commonly used prescription drugs can interrupt many weight regulating factors. When used long term (6 months or more), these drugs elicit obesity among most users. This is true despite rigorous workout or diet routines that may be employed. Ever met someone who exercised religiously yet failed to lose fat?
The most common of these drugs are those used to treat high blood pressure (beta blockers such as Atenolol), depression (SSRI's such as Zyprexa), and diabetes (sulfonylureas such as Amaryl and thiazolidinediones such as Avandia).
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